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More about Protein Language Models
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We briefly discuss a recent paper from Salesforce research using protein language models to design functioning enzymes.
Designing new protein sequences with the help of LLMs
Protein language models have gained in prominence over the last few years. A team from Salesforce research used their protein language model, Progen, to generate sequences for artificial lysozymes. Researchers then selected 100 sequences to synthesize and test and found that ~70 of the generated sequences worked in practice. Getting 70% biological activity from a computational method is a powerful milestone.
Interesting Links from Around the Web
https://www.science.org/content/blog-post/wonderful-progress-against-severe-lupus: An interesting write-up of recent progress made in treating serious Lupus.
https://www.amazon.com/dp/B0BTNSJRKD: A new book on using Haskell for production. Haskell engineers continue to push the boundary for turning Haskell and functional programming into a technology suitable for production engineering.
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Author: Bharath Ramsundar, Ph.D.
Editor: Sandya Subramanian, Ph.D.